What can I expect?

ADT is used in different circumstances to treat prostate cancer:
  1. Localized prostate cancer. If your cancer hasn’t spread outside the prostate, you may be given ADT before (neo-adjuvant) or after (adjuvant) surgery or radiotherapy depending on the stage and grade of the tumour.
  2. Locally advanced prostate cancer. If your cancer has spread just outside the prostate you will likely be given ADT after radiotherapy. Men who have adjuvant hormone therapy after external beam radiation therapy for prostate cancer live longer, both overall and without having a recurrence, than men who are treated with radiation therapy alone (NCI, 2014). 
  3. Advanced prostate cancer. If your cancer has spread to other parts of the body, ADT can help control growth of the cancer and manage symptoms. ADT will be used until the cancer stops responding to it and starts to grow again at which point it is called castration resistant prostate cancer (CRPC).
ADT is used in various ways to treat prostate cancer.
  • Single vs Combination ADT: Anti-androgens can be given on their own or combined with either a LHRH agonist or surgical removal of the testicles ADT can also be combined with other treatments such as chemotherapy or new types of hormone treatment such as abiraterone or enzalutamide.
  • Continuous vs Intermittent ADT: ADT can be given continuously or it may be stopped once the PSA number is lowered and stabilized and then restarted when the PSA number increases again (intermittent). Intermittent ADT can give men a break from some of the side effects of ADT, however it is not clear if intermittent is as effective as continuous ADT.

Prostate Cancer Awareness Month

Donate Now!

Subscribe to our free monthly e-newsletter!

* indicates required


PCC Spotlight
Prostate Cancer Canada launches first national program in radionuclide therapy

Toronto, June 27, 2018 – Canadian researchers are leading the future of treatment for men with advanced prostate cancer in this country, with a new Prostate Cancer Canada grant funded by the Movember Foundation.

Honouring dad this Father’s Day the Canadian way: In plaid

TORONTO, ON – (May 8, 2018) – Plaid replaces business-casual on Friday, June 15 as hundreds of thousands of Canadians don the iconic Canadian attire all to honour dad and end prostate cancer.

The Finger – A tried and true method to save lives

TORONTO, CANADA (May 8, 2018) – Every day, more and more methods to detect prostate cancer are being explored, but the tried and true methods of a digital rectal examination (DRE) – where a healthcare professional inserts a gloved finger into the rectum to check for abnormalities, paired with a blood test known as the prostate-specific antigen (PSA) test – which you can get through your family doctor, are still the long-standing proven ways to save a life.

Click here for news archive